Determination of cyclodextrin content using periodate oxidation by capillary electrophoresis
A simple and general method suitable for the determination of cyclodextrin content in various matrices is described. The proposed method involves selective cleavage of C-C bonds with vicinal hydroxyl groups by means of periodate (Malaprade’s reaction). The amount of produced iodate is monitored by capillary electrophoresis, Optimized electrophoretic conditions (20 mM disodium tetraborate with 1 …
